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Generic Imovane (Zopiclone)
Use:
Short-term (i.e. 7-10 consecutive days) insomnia therapy.
Use for more than 2-3 consecutive weeks requires complete re-evaluation of the patient.
Adults: 7.5 mg tablet just before retiring for the night.
Geriatrics, patients with impaired liver function or chronic respiratory insufficiency: 3.75-7.5 mg at bedtime, depending on acceptability and efficacy.
Contraindications:
Myasthenia, sleep apnea syndrome, severe hepatic insufficiency, previous paradoxical reactions to alcohol and/or sedative medications.
Precautions:
Not recommended in pregnant or nursing women. Safety-efficacy in patients under 18 years of age has not been established. Use with caution in patients with a history of substance or alcohol abuse, impaired renal or hepatic functions, severe pulmonary insufficiency, a history of seizures (avoid abrupt Zopiclone withdrawal), depression, elderly and/or debilitated patients.
Side effects:
Bitter taste, somnolence, confusion, amnesia or memory impairment, asthenia, euphoria, depression, bad breath, coated tongue.
Interactions:
Hepatic enzyme-inhibiting agents (e.g. Cimetidine, crythromycin) and other CNS-depressant drugs may enhance Zopiclone`s activity.
Patient tips:
Warn against concomitant use of alcohol or other CNS-depressant drugs. Caution drowsiness (NB driving).
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